KIT (T670I) (Human) Recombinant Protein
产品名称: KIT (T670I) (Human) Recombinant Protein
英文名称: KIT (T670I) (Human) Recombinant Protein
产品编号: P5571
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human KIT (NP_000213.1, 544 a.a. - 976 a.a.) T670I mutant partial recombinant protein with GST tag expressed in baculovirus infected Sf21 cells.
- Theoretical MW (kDa):
- 76
- Form:
- Liquid
- Preparation Method:
- Baculovirus infected insect cell (Sf21) expression system
- Purification:
- Glutathione sepharose chromatography
- Purity:
- 62 % by SDS-PAGE/CBB staining
- Activity:
- The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorecence-labeled substrate and Mg(or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip 3000. Substrate: Srctide. ATP: 1000 uM
- Storage Buffer:
- In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Loading 1 ug protein in SDS-PAGE
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 3815
- Protein Accession#:
- NP_000213.1
- Gene Name:
- KIT
- Gene Alias:
- C-Kit,CD117,PBT,SCFR
- Gene Description:
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- mast/stem cell growth factor receptor,proto-oncogene tyrosine-protein kinase Kit,soluble KIT variant 1
- Interactome
- Related Disease
- Acute Disease
- Aneuploidy
- Azoospermia
- Chronic Disease
- Constipation
- Disease Progression
- Gastrointestinal Stromal Tumors
- Genetic Predisposition to Disease
- Hematologic Neoplasms
- Hyperpigmentation
- Infertility, Male
- Leukemia, Myelocytic, Acute
- Leukemia, Myeloid
- Leukemia, Myeloid, Acute
- Leukemia, Promyelocytic, Acute
- Liver Neoplasms
- Lung Neoplasms
- Malignant melanoma
- Mastocytosis, Cutaneous