LYN (N-term) Peptide
产品名称： LYN (N-term) Peptide
英文名称： LYN (N-term) Peptide
产品编号： P2756
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of LYN.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human LYN.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity.
Baran CP, Tridandapani S, Helgason CD, Humphries RK, Krystal G, Marsh CB.J Biol Chem. 2003 Oct 3;278(40):38628-36. Epub 2003 Jul 25.
- 2.
- BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571.
Donato NJ, Wu JY, Stapley J, Gallick G, Lin H, Arlinghaus R, Talpaz M.Blood. 2003 Jan 15;101(2):690-8.
- 3.
- Lyn kinase is activated following thrombopoietin stimulation of the megakaryocytic cell line B1647.
Santini V, Scappini B, Grossi A, Gozzini A, Bonsi L, Pagliai G, Rossi Ferrini P, Bagnara GP.Haematologica. 2002 Dec;87(12):1242-7.
- Applications
- Western Blot (Tissue lysate)
- The LYN polyclonal antibody (Cat # PAB3431) is used in Western blot to detect LYN in mouse liver tissue lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with LYN polyclonal antibody (Cat # PAB3431) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Entrez GeneID:
- 4067
- Protein Accession#:
- P07948
- Gene Name:
- LYN
- Gene Alias:
- FLJ26625,JTK8
- Gene Description:
- v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
- Omim ID:
- 165120
- Gene Ontology:
- Hyperlink
- Other Designations:
- Yamaguchi sarcoma viral (v-yes-1) oncogene homolog,Yamaguchi sarcoma viral (v-yes-1) related oncogene homolog