GSK3B polyclonal antibody
产品名称: GSK3B polyclonal antibody
英文名称: GSK3B polyclonal antibody
产品编号: PAB12688
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of GSK3B.
- Immunogen:
- A synthetic peptide corresponding to C-terminus of human GSK3B.
- Host:
- Rabbit
- Reactivity:
- Bovine, Chicken, Human, Mouse, Rat
- Specificity:
- This antibody recognizes GSK3B.
- Form:
- Liquid
- Storage Buffer:
- In PBS, pH 7.2 (10% Proclin300)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (0.1-1 ug/mL)
ELISA (0.01-0.1 ug/mL)
Immunoprecipitation (2-5 ug/mL)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Highly potent and specific GSK-3beta inhibitors that block tau phosphorylation and decrease alpha-synuclein protein expression in a cellular model of Parkinson's disease.
Kozikowski AP, Gaisina IN, Petukhov PA, Sridhar J, King LT, Blond SY, Duka T, Rusnak M, Sidhu A.ChemMedChem. 2006 Feb;1(2):256-66.
- Application Image
- Western Blot (Tissue lysate)
- enlarge
- Immunohistochemistry
- Immunoprecipitation
- ELISA
- Entrez GeneID:
- 2932
- Gene Name:
- GSK3B
- Gene Alias:
- -
- Gene Description:
- glycogen synthase kinase 3 beta
- Omim ID:
- 605004
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene
- Other Designations:
- GSK3beta isoform,glycogen synthase kinase-3 beta
- Interactome
- Gene Pathway
- Alzheimer's disease
- Axon guidance
- B cell receptor signaling pathway
- Basal cell carcinoma
- Cell cycle
- Chemokine signaling pathway
- Colorectal cancer
- Endometrial cancer
- ErbB signaling pathway
- Focal adhesion
- Hedgehog signaling pathway
- Insulin signaling pathway
- Melanogenesis
- Neurotrophin signaling pathway
- Pathways in cancer
- Prostate cancer
- T cell receptor signaling pathway
- Wnt signaling pathway
- Related Disease
- Adenocarcinoma
- Alzheimer Disease
- Alzheimer disease
- Amphetamine-Related Disorders
- Anorexia Nervosa
- Bipolar Disorder
- Bone Diseases
- Breast cancer
- Breast Neoplasms
- Bulimia
- Cardiovascular Diseases
- Cognition
- Dementia
- Depressive Disorder
- Depressive Disorder, Major
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Disease Progression
- Drug Toxicity