ASGR1 Rabbit pAb (APR23353N)
产品名称: ASGR1 Rabbit pAb (APR23353N)
英文名称: ASGR1 Rabbit pAb (APR23353N)
产品编号: APR23353N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围:
分子量:Calculated MW: 29kDa/33kDa Observed MW: Refer to figures 细胞定位:Membrane, Secreted, Single-pass type II membrane protein 稀释方法:IHC 1:50 - 1:200 总结:This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.