GPR44 polyclonal antibody
产品名称： GPR44 polyclonal antibody
英文名称： GPR44 polyclonal antibody
产品编号： PAB13244
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of GPR44.
- Immunogen:
- A synthetic peptide corresponding to internal region 15 amino acids of human GPR44.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Cutting edge: chemoattractant receptor-homologous molecule expressed on Th2 cells plays a restricting role on IL-5 production and eosinophil recruitment.
Chevalier E, Stock J, Fisher T, Dupont M, Fric M, Fargeau H, Leport M, Soler S, Fabien S, Pruniaux MP, Fink M, Bertrand CP, McNeish J, Li B.J Immunol. 2005 Aug 15;175(4):2056-60.
- 2.
- Chemoattractant receptor-homologous molecule expressed on Th2 cells activation in vivo increases blood leukocyte counts and its blockade abrogates 13,14-dihydro-15-keto-prostaglandin D2-induced eosinophilia in rats.
Shichijo M, Sugimoto H, Nagao K, Inbe H, Encinas JA, Takeshita K, Bacon KB, Gantner F.J Pharmacol Exp Ther. 2003 Nov;307(2):518-25. Epub 2003 Sep 15.
- 3.
- CRTH2, an orphan receptor of T-helper-2-cells, is expressed on basophils and eosinophils and responds to mast cell-derived factor(s).
Nagata K, Hirai H, Tanaka K, Ogawa K, Aso T, Sugamura K, Nakamura M, Takano S.FEBS Lett. 1999 Oct 8;459(2):195-9.
- Entrez GeneID:
- 11251
- Protein Accession#:
- NP_004769
- Gene Name:
- GPR44
- Gene Alias:
- CD294,CRTH2,DP2
- Gene Description:
- G protein-coupled receptor 44
- Omim ID:
- 604837
- Gene Ontology:
- Hyperlink
- Gene Summary:
- G protein-coupled receptors (GPCRs), such as GPR44, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.[supplied by OMIM
- Other Designations:
- chemoattractant receptor homologous molecule expressed on T helper type 2 cells,chemoattractant receptor-homologous molecule expressed on TH2 cells
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