ADRA1A Pre-design Chimera RNAi
产品名称： ADRA1A Pre-design Chimera RNAi
英文名称： ADRA1A Pre-design Chimera RNAi
产品编号： H00000148-R05
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 邮编 : 11493
- 所在区域 : 台湾
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- Specification
- Product Description:
- Homo sapiens adrenergic, alpha-1A-, receptor (ADRA1A), transcript variant 1, mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_000680
- Target Region:
- Coding sequence
- Note:
- Position of the Chimera RNAi.
The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence. -
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 148
- Gene Name:
- ADRA1A
- Gene Alias:
- ADRA1C,ADRA1L1,ALPHA1AAR
- Gene Description:
- adrenergic, alpha-1A-, receptor
- Omim ID:
- 104221
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq
- Other Designations:
- G protein coupled receptor,OTTHUMP00000125313,adrenergic, alpha -1A-, receptor,adrenergic, alpha-1A-, receptor variant 1,adrenergic, alpha-1A-, receptor variant 3,adrenergic, alpha-1A-, receptor variant 5,adrenergic, alpha-1A-, receptor variant 8,adrenerg
- Related Disease
- Acute Disease
- Alzheimer Disease
- Alzheimer disease
- Attention Deficit Disorder with Hyperactivity
- Bronchial Hyperreactivity
- Cardiovascular Diseases
- Coronary Disease
- Depressive Disorder, Major
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Drug Toxicity
- Dyskinesia, Drug-Induced
- Edema
- Fibromyalgia
- Gastroparesis
- Genetic Predisposition to Disease
- Hyperlipoproteinemia Type II
- Hypertension