SLC22A3 Pre-design Chimera RNAi
产品名称： SLC22A3 Pre-design Chimera RNAi
英文名称： SLC22A3 Pre-design Chimera RNAi
产品编号： H00006581-R01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Homo sapiens solute carrier family 22 (extraneuronal monoamine transporter), member 3 (SLC22A3), mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_021977
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 6581
- Gene Name:
- SLC22A3
- Gene Alias:
- EMT,EMTH,OCT3
- Gene Description:
- solute carrier family 22 (extraneuronal monoamine transporter), member 3
- Omim ID:
- 604842
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. [provided by RefSeq
- Other Designations:
- EMT organic cation transporter 3,OTTHUMP00000017542,extraneuronal monoamine transporter,organic cation transporter 3,solute carrier family 22 member 3
- Related Disease
- Amphetamine-Related Disorders
- Cholestasis
- Coronary Artery Disease
- Diabetes Mellitus, Type 1
- Diabetic Nephropathies
- Disease Progression
- Genetic Predisposition to Disease
- Hypertension
- Kidney Failure, Chronic
- Lung Neoplasms
- Neoplasm Recurrence, Local
- Prostate cancer
- Prostatic Hyperplasia
- Prostatic Neoplasms
- Psychoses, Substance-Induced
- Pulmonary Disease, Chronic Obstructive
- Tobacco Use Disorder