Complement C4 monoclonal antibody
产品名称: Complement C4 monoclonal antibody
英文名称: Complement C4 monoclonal antibody
产品编号: MAB10281
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native Complement C4.
- Immunogen:
- Native purified Complement C4 from human plasma.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Affinity purification
- Storage Buffer:
- In PBS, pH 7.5 (0.02% sodium azide, 50% glycerol (v/v))
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Enzyme Immunoassay
- Entrez GeneID:
- 720
- Gene Name:
- C4A
- Gene Alias:
- C4,C4A2,C4A3,C4A4,C4A6,C4S,CO4,CPAMD2,MGC164979,RG
- Gene Description:
- complement component 4A (Rodgers blood group)
- Omim ID:
- 120810
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. [provided by RefSeq
- Other Designations:
- C4A anaphylatoxin,OTTHUMP00000029266,Rodgers form of C4,acidic C4,complement component 4A
- Related Disease
- Adrenal Hyperplasia, Congenital
- Adrenal hyperplasia, congenital
- Atherosclerosis
- Autoimmune Diseases
- Cardiovascular Diseases
- Coronary Artery Disease
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Edema
- Genetic Predisposition to Disease
- Liver Cirrhosis
- Lupus Erythematosus, Systemic
- Lymphoma, Non-Hodgkin
- Opportunistic Infections
- Purpura, Schoenlein-Henoch
- Recurrence